Of the other main rivals, New Approach finally gets his chance over 1m 4f, a trip he was bred to win over.
However, there is the worry that he may have had two very hard races in his build-up when defeated by Henrythenavigator in both the 2,000 Guineas and the Irish 2,000 Guineas.
Sir Michael Stoute poses a bigger danger to the selection with three progressive colts, each winners of their respective trials. Ryan Moore has plumped for Tartan Bearer, who showed a handsome turn of foot to win the Dante Stakes at York.
But his other pair, Doctor Fremantle and Tajaaweed, both have form that puts them in the picture.
Henry Cecil saddles his first Derby runner for eight years with Kandahar Run and, despite being around 16-1, he is no back number.
Aidan O'Brien runs five in the race with Johnny Murtagh surprisingly picking King Of Rome who was beaten by stablemate Alessandro Volta in the Lingfield Derby trial. Yet on form, Frozen Fire is possibly O' Brien's best hope.
There are so many unknowns about this race: how horses will handle Epsom, will they get the trip, is the ground okay etc, but the one thing we do know is it will take something special for any colt to end Casual Conquest's unbeaten run.