David Nalbandian cruised through the opening round in his defence of the Swiss indoor tournament in Basle.
The fourth seed from Argentina, returning from a wrist injury, enjoyed a 6-4, 6-0 win over Spain's Ruben Ramirez Hidalgo.
US Open champion Andy Roddick was stretched by Swiss qualifier Jean-Claude Scherrer before going through 6-3, 7-6.
Kim Clijsters reached the last eight of the Seat Open in Luxembourg with a 6-3, 6-1 win over Claudine Schaul.