In an attempt to calm the feminism row surrounding the museum, Mr Palmer-Edgecumbe added that he had deliberately employed female curators and historians.
"We are trying to do something new and historical. We have created a fully immersive experience - trying to understand what it feels like to live in the 1880s.
"I do not think there is any danger of people not understanding the historical significance and seriousness of what happened."
The museum, based in a converted Victorian house on Cable Street, consists of a series of rooms which have been created to tell the Ripper's story using police reports, newspaper cuttings and genuine artefacts from the time.
The basement morgue has real photographs of the victims' bodies, including Catherine Eddowes, who was gruesomely dismembered.
Former banker Mr Palmer-Edgecumbe, who previously sat on the boards of the Museum of London and the Docklands Museum, insists the morgue basement is not needlessly macabre.
He said: "To understand the seriousness of what happened you need to see these pictures.
"We do warn people what is in here - some parents choose not to bring their children in here, they have to make up their own minds.
"It might not be suitable for some people.
"But in many ways the pictures make it more powerful - they are the pictures of the dead women.
"If you know the lives of these women then it is incredibly sad. Most of them were buried in unmarked graves."
"I think Jack the Ripper is one of the integral parts of London history. I thought, why not take that story that everyone has heard of and tell it from a completely different perspective and actually look at it through the lives of his victims for the first time.
"It is very sad that those women are generally only a footnote to the story and it is just about how many women he killed and how horrifically were murdered.
"We try to look at their lives from when they were born to when they died."