Macdonald is better known for directing new plays by playwrights at the more radical, experimental end of the spectrum: Martin Crimp, Caryl Churchill and the late Sarah Kane (he directed the infamous premiere of Kane's play Blasted in 1995).
Ironically, he chose Exiles because 'I've never really done one of those big, old, nuts-and-bolts plays that you can take apart like a clock. And Henrik Ibsen [whose influence on Exiles is clear] has been done a lot recently.'
Instead, the more Macdonald explored Exiles, the more modern the play felt to him. 'It's like the sort of plays you get today in that it's full of ambiguity,' he says. 'You never peel away all the layers of what happens. There's a strong sense of people being exiled from themselves, and the impossibility of ever knowing someone else fully. And you can see the way that Joyce deals with characterisation running through Beckett and into Pinter and Churchill.
'Ultimately, the levels of honesty in the play are shocking. Joyce takes these great Ibsenite, social ideas about truth and freedom and applies them in a very personal, Joycean way. These ideas are in some respect unworkable. That is why the play is a comedy, and that is one of the things I love most about it.'
Exiles previews tonight and opens tomorrow, Cottesloe, National Theatre SE1, 7.30pm (tomorrow 7pm), mats 2.30pm £10 to £28. Tel: 020 7452 3000, www.nationaltheatre.org.uk. Tube: Waterloo, Embankment.