Shares slid by 9.95p to 332.25p at the close of play.
Insurer Hiscox saw shares fall after it warned investors it increased its predicted costs from Covid-19 by more than 50%.
Shares fell by 26.4p to 755.2p after it said it expects 232 million dollars (£178 million) will be needed to deal with virus-related claims.
Elsewhere, Metro Bank agreed to buy lender RateSetter in a deal worth up to £12 million, boosting its shares.
The high street challenger bank saw shares rise by 6.7p to 110p after it announced the deal to buy one of the country’s largest and oldest peer-to-peer lenders.
The biggest risers on the FTSE 100 were Lloyds, up 1.58p at 27.87p, Smurfit Kappa, up 136p at 2,676p, Natwest, up, 5.05p at 111.05p, and Intertek, up 244p at 5,622p.
The biggest fallers of the day were HSBC, down 9.95p to 332.25p, BT Group, down 0.56p at 98.02p, IAG, down 0.9p ay 163.85p, and Rolls-Royce, down 1.2p at 230.4p.