Such an inference would imply that jockeys and trainers are deliberately preventing horses winning.
But Wilson, again without providing any worthwhile evidence, feels the net spreads wider than just those closest to the horse.
"There are more people connected with a horse than just the jockey and trainer who can influence its running," he added.
"Exchanges have been brilliantly marketed and even the government have given them their tacit approval, but I have been opposed to them from day one and I feel they should be blown out of the water."
Betfair spokesman Mark Davies described Wilson's criticism as "misguided at best".
He added: "Julian has a long history in racing and I normally have a lot of respect for him. I don't want to rubbish his views, but on this occasion you can drive a coach and horses through his arguments."
Wilson's comments come at a time when the potential threat to racing's integrity posed by exchanges is coming under increasing scrutiny.
Leading on-course bookmaker Barry Dennis alleged this week that the Jockey Club have no teeth to deal with the issue, while Lancashire blacksmith Steve O'Sullivan is pencilled-in to appear at Portman Square next Thursday for an inquiry to investigate his involvement with a series of market 'drifters' which he is alleged to have laid heavily on the exchanges.
Meanwhile, the shape of Saturday's Hennessy Gold Cup at Newbury has still to be finalised as connections eye the weather forecasts.
Paul Nicholls looks all set to run his exciting novice Strong Flow now that the ground is on the easy side, but Henry Daly warned punters to hold fire over Haut Cercy.
The eight-year-old signed off last season with a fine second behind Youlneverwalkalone at the Cheltenham Festival, but Daly will bypass the Hennessy if the forecast for further rain proves accurate,
He said: "He's very well, but all his best form is on faster ground and it's going to be a case of seeing what the weather does overnight before we decide whether he can run or not."