Milan are Italy's most successful European Cup competitors with six wins, the first in 1963 and the most recent in 2003 when they beat Juventus on penalties at Old Trafford.
Juve, of course, will be highly fancied to progress further after David Trezeguet and Marcelo Zalayeta scored the goals that knocked out Real Madrid in a fractious second leg in Turin.
Despite winning 27 Italian titles, Juve have won Europe's biggest prize only twice, most recently in 1996 when they beat Holland's Ajax on penalties.
The only Dutch survivors in the last eight are PSV Eindhoven, who followed up a 1-0 home-leg victory with last night's impressive 2-0 win at last season's beaten finalists, Monaco.
PSV won the European Cup under Gus Hiddink in 1988. With him back in charge, they qualified from the group stage for the first time in eight years this season thanks largely to a home draw with Arsenal.
Bayern Munich, conquerors of Arsenal, have reached the last eight for the first time for three years. They are Germany's most successful European Cup team, having lifted the crown four times. Their most recent triumph was in 2001, when they beat Valencia on penalties.
Lyon topped their qualifying group ahead of Manchester United. They then humiliated Werder Bremen with a 10-2 aggregate win - Sylvain Wiltord scoring a hat-trick in the second leg - to clinch a place in the last eight.
It was in the quarter-finals last season that they were beaten by eventual winners Porto, who face Inter Milan, twice winners of the competition, in their delayed second leg on March 15. They drew the first leg, in Portugal, 1-1.
Last season Mourinho's Porto avoided the big guns in the latter stages - beating Lyon, then Deportivo in the semifinals and Monaco in the final. The Chelsea coach will be a very lucky man if it's as straightforward this time.
Quarter-finalists Chelsea, Liverpool Juventus, PSV Eindhoven AC Milan, Bayern Munich, Lyon, Inter Milan or Porto (Tuesday)