"The one thing I would say is that this is a completely different situation from prior F1 teams stopping," he said.
"This team is one of the best funded, has the best assets, the best resources in the pit lane, a fantastic group of people and a car designed by Ross Brawn which is ready to go next year.
"I think we are going to be a desirable asset for somebody."
The public face of F1, commercial rights holder Bernie Ecclestone, is also confident that Honda will find a buyer and said today: "I think it's okay. I think there's a number of people out there that have shown a lot of interest."
But he accepts money is becoming tight in his sport and added that Honda's withdrawal was a wake-up call for F1.
He warned: "Both Max Mosley and myself have been campaigning now for quite a long time to try to reduce the necessity to spend vast amounts of money to be competitive.
"When you consider that Honda have got 700 people working there to put two cars on the starting grid, it's a little bit cranky."
The withdrawal of Honda came as no surprise to Mosley himself and the FIA chief hopes to use the current situation as a spur to teams to accept his cost- cutting proposals.
He said: "I've been expecting one of the major manufacturers to stop. Now it's difficult to imagine how any manufacturer could stay in unless we make substantial reductions in costs."
Mosley's primary suggestion is to offer a standardised engine, made by Cosworth, to all teams from the start of 2010 at a cost of £5.5m per season.
Teams turning down the offer would have the choice of either developing their own new engine — as long as it follows the the Cosworth specifications — or continuing with their engines while observing the existing ban.