"The season before, we were already qualified when we went to Galatasaray for the last match and we were able to use other players.
"The atmosphere was so different. If we can go to PSV Eindhoven for our final group match with our place in the knock-out stage decided, we can use young players.
"The Champions League is massive and we must progress. Hopefully we can make sure of our qualification in this match and then be able to concentrate on the Premier League."
Benitez will overtake Bill Shankly for the most European matches overseen by an Anfield manager this evening.
This will be his 66th European tie with the Reds and he said: "I am really proud to be in such a position, so hopefully the next 66 games I will be here as well.
"This amount of European games is a good achievement for anyone but especially when you are talking about a top side like Liverpool. That also means the team are doing well in Europe and that is very positive for the club."
Benitez will have captain Steven Gerrard back from his torn groin muscle to face Marseille, who will include former Liverpool winger Boudewijn Zenden.
The Dutchman said: "Liverpool are a team in the top two in England. It'll be very difficult but we are not afraid."
