This was particularly a golden opportunity blown because in the preceding heat, the Americans, favourites along with the Usain Bolt-inspired Jamaicans, had also crashed out on the last changeover - with Darvis Patton and Tyson Gay conspiring to spill the stick.
Astonishingly, the US women's quartet had a similar calamity, failing to finish their heat, but the British foursome of Jeanette Kwakye, Montell Douglas, Emily Freeman and Emma Ania made it to the final, second in that same semi in 43.02sec.