Edu will now partner Ray Parlour in central midfield with Robert Pires and Fredrik Ljungberg providing the width. Up front, Nwankwo Kanu will play behind Thierry Henry while Kolo Toure stays at right-back with Pascal Cygan alongside Sol Campbell in central defence.
If Arsenal fail to make it to the next round, losing out on £10million in revenue, Wenger will not have massive funds to spend in the transfer market in January.
In the other match Lokomotiv Moscow kick off against Dynamo Kiev at 5.30pm.