The Samoan known as 'Inga the winger' said: 'I'm excited to be going back to Twickenham. Potentially, we are a better side than two years ago and we're starting to see the fruits of all our work.
'These young players make us older guys try that bit harder just to keep up with them.
'I was just fortunate enough to be in the right place at the right time for those tackles. I've always relished the physical side of the game and I must admit I did go looking for my cousin, Apollo, and we had a plan to try to starve Jason Robinson of the ball.'
May's strength helped him over for his first try when Dave Walder took a quick tap penalty after Ross Beattie had charged over from close range for Newcastle's opening try.
With Wilkinson's radar spot-on, Newcastle seemed to be cruising in until Charlie Hodgson shot over in the corner to give Sale some hope.
May's second try, when he charged over from 45 metres, stretched Newcastle's lead to 34-13 before Sale hit back with tries from Duncan Bell and Steve Hanley.
However, Wilkinson made it safe with his final penalty in a 22-point display.