Yet Mertesacker said rotation would be important with a tough run of fixtures approaching, including league matches against Liverpool, Manchester United, Tottenham Hotspur, Chelsea, Manchester City and Everton in the next two months.
"But I wouldn't say that's only us or the two of us. I think when I speak about our centre backs I want to include always Thomas Vermaelen because he's our captain and he's always vital for everyone. He's aware of situations, he gives us a boost, he came back from a heavy injury.
"The boss will rotate in the next couple of months and it's really important that we are all in good fitness and all in a good shape so we can continue our good form and good partnerships with the three of us."
Goalkeeper Wojciech Szczesny, who fought back from being dropped by manager Arsene Wenger last season to establish himself as the undisputed number one at the Emirates Stadium, said consistency of selection was key to their strong performances this season.
"We've been together for much longer and we understand each other's game now," the Poland international said.
"Over the last couple of seasons we had less luck with injuries - I never played with the same back four for more than two or three games (in a row).
"Now we play with the same back four, sometimes we rotate the fullbacks but in general we stay with the same defence."
