The point is not lost on their players, several of whom will play through the pain of ongoing injuries.
Manager Martin Allen said: "It is a massive game in the club's history. It offers so many motivational positives for the players. Staying in the Second Division gives them a much better opportunity of playing at a higher level."
Brentford were bailed out of a financial crisis two years ago when supporters' trust Bees United raised enough cash to keep the club out of administration without the need to sell Griffin Park.
Bees United aim to keep the club in business to realise the dream of a new stadium at Kew Bridge. Relegation, however, would be a major setback.
Captain Michael Dobson is available after recovering from a back injury.
Brentford v Bournemouth, Griffin Park, tomorrow, 3pm
