During a lunar eclipse, the moon turns a deep rusty red, due to sunlight being scattered by the Earth's atmosphere.
Through the ages, so-called "blood moons" have been viewed as ill omens by superstitious people.
Anyone staying up to see the red moon is in for "quite an unusual sight", according to the Society for Popular Astronomy vice president Robin Scagell.
His tips are to arm yourself with binoculars and look out for the deep redness in the sky when the moon is fully in shadow.
The shade will depend on the atmospheric conditions, and there may be a bluish tinge at the moon's edge.
Unlike with a solar eclipse, a lunar eclipse is completely safe to observe through binoculars or a small telescope.
Many believe this eclipse is significant as it marks the completion of an unusual line-up of four total eclipses at six-monthly intervals known as a "tetrad".
Texan pastor and author John Hagee says this has only happened three times in the past 500 years and claims it is likely to herald a "hugely significant" world event.
