One journey in every 513,000 now ends in death or serious injury, beating the previous low of 2006 when it was one journey in every 434,000.
The number of KSIs - the standard measurement - has fallen by almost 80 per cent since 1989, the peak year, when 33 cyclists were killed and 752 seriously injured on London’s roads.
However, the TfL safety figures also showed a rise in the number of cyclists suffering slight injuries, up 14 per cent to 4,714 from 4,134 in 2013.
Operation Safeway, the Met’s highway safety operation which targets road users committing traffic offences, has been credited in part for helping to improve driver and cyclist behaviour.
Mr Johnson admitted: “But we need to do more.”
His Safer Lorry Scheme, which will ban all lorries not fitted with safety equipment from London’s roads, will start within three months.
He has also brought in segregated cycle superhighways, improved junctions and Quietway back- street cycle routes as part of a £913 million investment programme.
“The cyclist population explosion in London shows why we need all this and why we need to go still further,” he added.
However, Mr Johnson has been accused of a “massive underspend” on his cycling budget and criticised for failing to target many cycling casualty hotspots with his better junctions programme.
Rosie Downes, from the London Cycling Campaign, said: “It is heartening that the number of people killed or seriously injured while cycling has fallen, but the figures are still unacceptably high.
“The growth in cycling is welcome, and highlights the urgent need for London’s streets to offer safe space for cycling for all.
“Better infrastructure is desperately needed to reduce the danger for the increasing number of people who cycle, or who would like to cycle, in London.”
