Margaret Toomey, a member of Bromley and Bexley Green Party, who has been giving out leaflets for campaign group Japanese Against Nuclear UK for the past 18 months, said: "We're here today because it's the third anniversary.
"The four nuclear reactors are emitting 400 tonnes (of dangerous waste) per day into the North Pacific and the company is using poor people to try and repair the nuclear reactors but things are the same as they were three years ago. There was another leak three weeks ago in a storeroom. That waste was pushed into the North Pacific."
During the march, there were individuals dressed as nuclear waste barrels which they hoped would highlight the fact that nuclear power created nuclear waste.
Curious onlookers on Piccadilly Road were accosted by some of the marchers explaining the purpose of the march and handing out leaflets.
As the march continued towards Piccadilly Circus, the fluorescent yellow banners and flags dominated the road and tourists looked on with amazement.
Members of the public who took leaflets could be heard agreeing that change was needed with regards to attitudes towards nuclear power.
Leaflets produced by Japanese Against Nuclear UK (JAN) gave a winter update about deadly spent fuel rods being removed from reactor number four at Fukushima.
According to JAN, 1,553 bundles of rods have to be removed which will take a year to complete if the rate of 44 bundles a week continues.
But the leaflet warns: "And if something 'unfortunate' does happen, it is quite likely to lead to Tokyo having to be abandoned, and a few million extra cancer cases around the world."