Powley was born in Shepherd’s Bush, the daughter of an actor (Mark Powley, whose CV includes The Bill, Casualty and Hollyoaks) and a casting director (Janis Jaffa) who, despite their jobs, were pretty horrified when their daughter was cast from her drama class as the lead in the CBBC show MI High at the age of 14. ‘They were like, “Oh God, no, we thought she was going to be the academic one and go to university.”’ For her part, the ‘super geeky’ Powley thought she was being ‘savvy by doing this little TV show and saving money to go to uni’. But then she landed a role in her first theatre production, Polly Stenham’s Tusk Tusk at the Royal Court, and the acting bug kicked in full throttle, with another Stenham play and a production of Tom Stoppard’s Arcadia on Broadway following when she was 19. After that, she was supposed to embark on a degree, but ‘kind of kept deferring... for three years’. During those three years, she was steadily notching up TV parts (Benidorm, The Bill) before landing her breakthrough role in Marielle Heller’s The Diary of a Teenage Girl. She was 22. Mr and Mrs Powley gave up any hope of their daughter going to university.