The removal of pillars gives the dance floor an airy warehouse vibe, it's less cluttered and the DJ booth now occupies one of the two long walls, while a tiered dancing stage — evoking the popular Rizla Arena found at festivals — sits opposite.
Crucially DJs are no longer elevated and distant but on the same level as the dance floor and within easy reach for the high fives and bumping fists of their appreciative audience.
"After a fire wiped out the main room back in the spring it was a chance to improve on things — we thought, what makes a good night?" explains manager Ben Kreeger.
"Fundamentally it's about good sound and flashing lights in a no-nonsense space. So we stripped the main room right back, which makes it feel bigger. It's a more flexible space capable of hosting clubs and gigs."
As the opening weekend with Hot Chip (Fri), Goldie (Sat) and Skream and Benga (Sun) demonstrates, Plan B's programming champions cool, cutting-edge club music.
"We had got a bit stale, but we won't be hosting the old names any more. Instead we're working with some very interesting promoters, like Snap Crackle & Pop and Deadly Rhythm," said Kreeger.
Forthcoming line-ups bear this out: tomorrow night Plan B hosts the after-party (one for the hardcore among you, from 4am-10am) for Swedish House Mafia's Brixton Academy gig with Steve Angello and Sebastian Ingrosso headlining House Rules, and Sunday weekly B:low is south London's answer to Fabric's Wet Yourself with minimal electro and house until 6am (15 Nov).
Other highlights this month include Tilt with Justin Robertson and the Filthy Dukes (21 Nov), Deadly Rhythm featuring bass auteur Kode9 and maverick Zomby (27 Nov), and Lesson1 starring DJ Yoda and Yoyo's Seb Chew (28 Nov).
Bugz In The Attic do a full live show (14 Nov), and gigs will become a major element of Plan B's repertoire on Wednesdays and Thursdays next year — Lee Scratch Perry and The Herbaliser's shows are already linked in the diary.
It will surely only be a matter of time before word spreads beyond south London and the capital's clubbers realise that Plan B's on-point programming, top-notch sound, dazzling lighting and a 24-hour licence means it's actually a "Plan A" electronic music destination.