In January in the US, Astra lost exclusivity to Nexium, which is used to treat gastroesophageal reflux and accounted for $641 million in revenue in the third quarter.
Astra is continuing to invest in research and development and has increased its spending from $1.3 billion to $1.4 billion on an annual basis.
The company has promised investors its new cancer treatments will help it return to growth by 2017.